Grigori G. Martinovich

Position held: Head of the Department

Degree, academic title:Doctor of Biological Sciences, Associate Professor

Specialization:Кафедра биофизики

Contact Information:
The address: Minsk, 5, Bobruiskaya st., office 548
Phone: +375 (17) 209-54-46
E-mail: MartinovichGG@bsu.by



Brief information:

 

1992-1997 - studies at BSU (Faculty of Physics)
1997-1998 - Master's degree studies at BSU
1998-2001 - postgraduate studies at BSU
2001 - Junior Researcher, BSU
2004 - defended his Ph.D. thesis in the specialty "Biophysics"
2004 - Assistant at the Department of Biophysics, BSU
2006 - Senior Lecturer, Department of Biophysics, BSU
2008 - Associate Professor at the Department of Biophysics, BSU
2009 - awarded the title of Associate Professor
2014 - defended his doctoral dissertation in the specialty "Biophysics"
2015 - Professor of the Department of Biophysics, Faculty of Physics, BSU
Since 2017 - Head of the Department of Biophysics, Faculty of Physics, BSU

 

Teaching disciplines:

Cell Biophysics
Physics of Biosystems
Photonics of biological objects
Bioenergy and Metabolism
Fundamentals of Medical Biophysics and Nanomedicine
Bioengineering: Molecular and Cellular

 

Areas of scientific interest:

Medical Biophysics
Cancer Biophysics
Oxidative stress and redox regulation
Cell signaling mechanisms

 

Honorary awards, prizes:

Prize of the National Academy of Sciences of Belarus for young scientists, 2005

Scholarship of the President of the Republic of Belarus for talented young scientists, 2007

BSU Certificate of Honor, 2015

Certificate of Honor of the Ministry of Health of the Republic of Belarus, 2018

Scholarship of the President of the Republic of Belarus for talented young scientists, 2019

The A.N. Sevchenko Prize in the field of Natural and Technical Sciences in the nomination "Science", 2019

The Makariev Prize in Natural Sciences, 2020

Certificate of Honor of the National Academy of Sciences of Belarus, 2022

 

 

Main publications:

 

Books:

 

  1. Martinovich G.G., Sazanov L.A., Cherenkevich S.N. Cellular Bioenergy: Physicochemical and Molecular Basics. Moscow: LENAND, 2017.200 s.

  2. Martinovich G.G., Cherenkevich S.N. Redox processes in cells. Mn .: BSU, 2008.159 p.

  3. Cherenkevich S.N., Martinovich G.G., Khmelnitsky A.I. Biological membranes. Mn .: BSU, 2009.184 p.

 

 

Articles:

 

  1. Martinovich G.G., Drapeza A.I., Cherenkevich S.N. Physicochemical converter for a neurochip based on a planar capacity // Bulletin of the Belarusian Engineering Academy. 1997. N 1 (3) / 3. p.152-155.

  2. Denisov A.A., Martinovich G.G., Molchanov P.G., Drapeza A.I., Cherenkevich S.N., Gurin V.N. Measurement of electrical characteristics of nerve cells and tissues using sensors based on MOS transistors // Reports of the Academy of Sciences of Belarus. 2000. Volume 44. No. 6. p.53-55.

  3. Cherenkevich S.N., Martinovich G.G. Regulation of neurite growth // Advances in physiological sciences. 2001. Volume 32. No3. P.23-39.

  4. Martinovich G.G., Cherenkevich S.N., Denisov A.A., Molchanov P.G., Gleb S.P. Modification of calcium homeostasis in model C6 and PC12 cells under oxidative stress // Vesti NAS Belarus. Ser. honey-b_yal. navuk. 2002. No. 4. C.70-76.

  5. Kukcharenko L.V., Fuch H., Ilyich G.K., Gronskaya R.I., Cherenkevich S.N., Martinovich G.G. Scanning Force Microscopy Study of PC12 Cells Surface Morphology // Phys. Low- Dim. Struct. 5/6 (2002). Pp.115-120.

  6. Martinovich G.G., Cherenkevich S.N., Denisov A.A., Molchanov P.G., Bulay P.M. Electrical activity of isolated ganglia of the mollusk Lymnaea stagnalis under the action of hydrogen peroxide // Vestn. Belarusian. un-that. Ser. 2. 2003. No. 3. C.17-23.

  7. Martinovich G.G., Cherenkevich S.N. Intracellular effective redox potential & ndash; new factor of regulation of cellular processes // Vestn. Belarusian. un-that. Ser. 1. 2004. No. 1. C.28-36.

  8. Martinovich G.G., Cherenkevich S.N. Redox buffer capacity of biosystems // Vestn. Belarusian. un-that. Ser. 1. 2004. No. 3. C.14-19.

  9. Cherenkevich S.N., Martinovich G.G., Drapeza A.I., Martinovich I.V., Loban V.A., Lisichenok A.N. Cell technologies and their application in medicine // Healthcare. 2004. No6, P.26-32.

  10. Martinovich G.G., Cherenkevich S.N. Utilization of hydrogen peroxide by epithelial cells of the human amnion // Biomedical chemistry. 2005. Vol.51. No. 6. P.626-633.

  11. Martinovich G.G., Cherenkevich S.N., Sauer H. Intracellular redox state: towards quantitative description // Eur. Biophys. J. 2005. Vol. 34. No. 7. P. 937-942.

  12. Cherenkevich S.N., Martinovich G.G. Reactive oxygen species and regulation of cellular functions // Vestn. GrSU them. I. Kupala. Series 2. 2008. No. 1. & ndash; P.109-117.

  13. Martinovich G.G., Martinovich I.V., Cherenkevich S.N. Signal transduction with the participation of calcium ions in BGM and C6 cells under the action of hydrogen peroxide // Vestn. GrSU them. I. Kupala. Series 2. 2008. No. 3. C.150-155.

  14. Martinovich G.G., Cherenkevich S.N. Redox homeostasis of cells // Advances in physiological sciences. 2008, volume 39, №3, pp. 29-44.

  15. Martinovich G.G., Martinovich I.V., Cherenkevich S.N. Quantitative characteristics of the redox state of erythrocytes // Biophysics. 2008, volume 53, no. 4, pp. 618-623.

  16. Martinovich G.G., Martinovich I.V., Cherenkevich S.N. Effects of ascorbic acid on calcium signaling in tumor cells // Bull Exp. Biol. Med. 2009. Vol.147, No. 4, P.469-472.

  17. Martinovich G.G., Martinovich I.V., Golubeva E.N., Cherenkevich S.N. The role of hydrogen ions in the regulation of the redox state of erythrocytes // Biophysics. 2009, volume 54, no. 5, pp. 846-851.

  18. Cherenkevich S.N., Martinovich G.G., Martinovich I.V., Golubeva E.N. Redox homeostasis of biological systems: theory and experiment. // Journal of the State Medical University. 2009. No. 2, p. 9-11.

  19. Martinovich G.G., Martinovich I.V., Cherenkevich S.N., Sauer H. Redox buffer capacity of the cell: theoretical and experimental approach // Cell Biochem Biophys. 2010. Vol.58, No.2, P.75-83.

  20. Shamova E.V., Gorudko I.V., Drozd E.S., Chizhik S.A., Martinovich G.G., Cherenkevich S.N., Timoshenko A.V. Redox regulation of morphology, cell stiffness, and lectin-induced aggregation of human platelets // Eur Biophys J. 2011, Vol. 40. # 2. P. 195-208.

  21. Martinovich G.G., Martinovich I.V., Cherenkevich S.N. Redox regulation of cellular processes: a biophysical model and experiment // Biophysics. 2011. Vol.56, No. 3, P.444-451.

  22. Martinovich G.G., Martinovich I.V., Golubeva E.N., Cherenkevich S.N., Demidchik Yu.E., Gain Yu.M., Vladimirskaya T.E., Lushchik M.L. Redox biotechnology as a basis for a new strategy in anticancer therapy // Izvestia of the National Academy of Sciences of Belarus. Ser. honey. sciences. 2012. No. 2. P.85-104.

  23. Martinovich G.G., Golubeva E.N., Martinovich I.V., Cherenkevich S.N. Redox regulation of calcium signaling in cancer cells by ascorbic acid involving the mitochondrial electron transport chain // Journal of Biophysics, vol. 2012, Article ID 921653

  24. Cherenkevich S.N., Martinovich G.G., Martinovich I.V., Gorudko I.V., Shamova E.V. Redox regulation of cellular activity: concepts and mechanisms // Bulletin of the National Academy of Sciences of Belarus. Ser. biol. sciences. 2013. No. 1. P.92-108.

  25. Martinovich G.G., Martinovich I.V., Zenkov N.K., Menshchikova E.B., Kandalintseva N.V., Cherenkevich S.N. Phenolic antioxidant TS-13 regulating ARE-driven genes induces tumor cell death by a mitochondria-dependent pathway // Biophysics. 2015. Vol.60, No. 1, P.94-100.

  26. Martinovich G.G., Martinovich I.V., Menshchikova E.B., Zenkov N.K., Cherenkevich S.N. Redox properties of tumor cells and their proliferative activity under the action of phenolic antioxidants // Reports of the National Academy of Sciences of Belarus. 2015. Vol.59, No. 3. P.82-87.

  27. Zenkov N.K., Chechushkov A.V., Kozhin P.M., Kandalintseva N.V., Martinovich G.G., Menshchikova E.B. Plant phenols and autophagy // Biochemistry (Moscow). 2016, Vol. 81, No. 4, R. 297-314.

  28. Martinovich G.G., Martinovich I.V., Vcherashnaya A.V., Shadyro O.I., Cherenkevich S.N. Differential regulation of the production of reactive oxygen species and mechanisms of tumor cell death by para-benzoquinones // Reports of the National Academy of Sciences of Belarus. 2016. Volume 60. No5, p. 96-100.

  29. Martinovich G.G., Martinovich I.V., Vcherashniaya A.V., Shadyro O.I., Cherenkevich S.N. Thymoquinone, a biologically active component of Nigella sativa, induces mitochondrial production of reactive oxygen species and programmed death of tumor cells // Biophysics. 2016, Vol. 61, No. 6, pp. 963 & ndash; 970.

  30. Zenkov N.K., Chechushkov A.V., Kozhin P.M., Kandalintseva N.V., Martinovich G.G., Menshchikova E.B. Mazes of Nrf2 Regulation. // Biochemistry (Moscow). 2017, Vol. 82, No. 5, R. 556-564.

  31. Martinovich G.G., Martinovich I.V., Vcherashniaya A.V., Zenkov N.K., Menshchikova E.B., Kandalintseva N.V., Cherenkevich S.N. Mechanisms of redox regulation of chemoresistance in tumor cells by phenolic antioxidants. // Biophysics. 2017. Vol. 62, No.6, pp.942-949.

  32. Gainutdinov P.I., Kozhin P.M., Chechushkov A.V., Martinovich G.G., Holshin S.V., Kandalintseva N.V., Zenkov N.K., Menshchikova E.B. An inverse relationship between the antioxidant activity of synthetic monophenols of a structurally related series and their toxicity towards tumor cells. // Siberian Scientific Medical Journal. 2018. Volume 38. No1, pp. 22-31.

  33. Martinovich G.G., Martinovich I.V., Vcherashnaya A.V., Zenkov N.K., Menshchikova E.B., Cherenkevich S.N. Regulation of proliferative activity and chemoresistance of tumor cells with sodium ascorbate. // Dokl. Nat. acad. sciences of Belarus. 2018.Vol. 62.No. 1, p. 93 & ndash; 100.

  34. Martinovich G.G., Martinovich I.V., Vcherashnaya A.V., Zenkov N.K., Menshchikova E.B., Cherenkevich S.N. Biophysical and molecular mechanisms of redox regulation of chemoresistance of tumor cells // Actual problems of biological physics and chemistry. 2018. Volume 3. No. 2, pp. 379-383.

  35. Menshchikova E.B., Zenkov N.K., Kozhin P.M., Chechushkov A.V., Kovner A.V., Khrapova M.V., Kandalintseva N.V., Martinovich G.G. Synthetic phenolic antioxidant TS-13 suppresses the growth of Lewis lung carcinoma and potentiates oncolytic effect of doxorubicin // Bulletin of experimental biology and medicine, 2019, Vol. 166, No. 5, pp. 646-650.

  36. Zenkov N.K., Kozhin P.M., Yesterday A.V., Martinovich G.G., Kandalintseva N.V., Menshchikova E.B. Features of redox regulation in tumor cells // Siberian Scientific Medical Journal. 2019, Volume 39. No. 9, pp. 11-26.

  37. Menshchikova E.B., Chechushkov A.V., Kozhin P.M., Kholshin S.V., Kandalintseva N.V., Martinovich G.G., Zenkov N.K. Activation of Autophagy and Nrf2 Signaling in Human Breast Adenocarcinoma MCF-7 Cells by Novel Monophenolic Antioxidants // Cell Tiss. Biol. 2019, Vol. 13, No. 2, P. 85-92.

  38. Zenkov N.K., Chechushkov A.V., Kozhin P.M., Martinovich G.G., Kandalintseva N.V., Menshchikova E.B. Autophagy as a defense mechanism against oxidative stress. Bulletin of Siberian Medicine. 2019, Volume 18.No.2, pp. 195-214.

  39. Zenkov N.K., Kozhin P.M., Chechushkov A.V., Kandalintseva N.V., Martinovich G.G., Menshchikova E.B. Oxidative stress during aging // Advances in gerontology. 2020.Vol. 33, No. 1. P. 10 & ndash; 22.

  40. Vcherashniaya A.V., Martinovich I.V., Martinovich G.G., Shadyro O.I., Cherenkevich S.N. A Raman Spectroscopic Study of Thymoquinone Antitumor Action. // Journal of Applied Spectroscopy. 2020. Vol. 87, No. 3.P. 515-519.

  41. Martinovich G.G., Martinovich I.V., Vcherashnaya A.V., Zenkov N.K., Menshchikova E.B., Cherenkevich S.N. Chemosensitization of tumor cells by phenolic antioxidants: the role of the Nrf2 transcription factor // Biophysics. 2020. Volume 65, No. 6. pp. 1081-1092.

 

Links to WEB resources:

http://www.scopus.com/authid/detail .uri? authorId = 6505991083

http://www.elibrary.ru/author_items.asp?authorid=643053

 

Profiles in scientometric databases:

http://www.researchgate.net/profile/Grigory_Martinovich/ ? ev = prf_highl

http://scholar.google.com/citations? user = hItiKUcAAAAJ & amp; hl = ru & amp; oi = ao

http://orcid.org/0000-0003-1972-6891