Grigori G. Martinovich

Position held: Head of the Department

Degree, academic title:Doctor of Biological Sciences, Associate Professor

Specialization:Кафедра биофизики

Contact Information:
The address: Minsk, 5, Bobruiskaya st., office 548
Phone: +375 (17) 209-54-46
E-mail: MartinovichGG@bsu.by



Brief information:

Short biography: 1992-1997 - studies at BSU (Faculty of Physics)
1997-1998 - Master's degree studies at BSU
1998-2001 - postgraduate studies at BSU
2001 - Junior Researcher, BSU
2004 - defended his Ph.D. thesis in the specialty `` biophysics ''
2004 - Assistant at the Department of Biophysics, BSU
2006 - Senior Lecturer, Department of Biophysics, BSU
2008 - Associate Professor at the Department of Biophysics, BSU
2009 - awarded the title of Associate Professor
2014 - defended his doctoral dissertation in the specialty `` biophysics ''
2015 - Professor of the Department of Biophysics, BSU
2017 - Head of the Department of Biophysics, BSU

Awards:
2005 - laureate of the prize of the National Academy of Sciences of Belarus for young scientists
2007 - a scholarship of the President of the Republic of Belarus was awarded to talented young scientists
2015 - awarded with the BSU Certificate of Honor
2018 - awarded with the Certificate of Honor of the Ministry of Health of the Republic of Belarus
2019 - a scholarship of the President of the Republic of Belarus for talented young scientists has been appointed
2019 - laureate of the I. A.N. Sevchenko in the field of natural and technical sciences in the nomination `` Science ''
2020 - Laureate of the Makariev Prize in Natural Sciences
Courses taught: Cell Biophysics
Physics of Biosystems
Photonics of biological objects
Bioenergy and Metabolism
Fundamentals of Medical Biophysics and Nanomedicine
Bioengineering: Molecular and Cellular
Scientific work: Medical Biophysics
Cancer Biophysics
Oxidative stress and redox regulation
Cell signaling mechanisms
Key publications: Books:
1. Martinovich G.G., Sazanov L.A., Cherenkevich S.N. Cellular Bioenergy: Physicochemical and Molecular Basics. Moscow: LENAND, 2017.200 s.
2. Martinovich G.G., Cherenkevich S.N. Redox processes in cells. Mn .: BSU, 2008.159 p.
3. Cherenkevich S.N., Martinovich G.G., Khmelnitsky A.I. Biological membranes. Mn .: BSU, 2009.184 p.

Articles:
1. Martinovich G.G., Drapeza A.I., Cherenkevich S.N. Physicochemical converter for a neurochip based on a planar capacity // Bulletin of the Belarusian Engineering Academy. 1997. N 1 (3) / 3. p.152-155.
2. Denisov A.A., Martinovich G.G., Molchanov P.G., Drapeza A.I., Cherenkevich S.N., Gurin V.N. Measurement of electrical characteristics of nerve cells and tissues using sensors based on MOS transistors // Reports of the Academy of Sciences of Belarus. 2000. Volume 44. No. 6. p.53-55.
3. Cherenkevich S.N., Martinovich G.G. Regulation of neurite growth // Advances in physiological sciences. 2001. Volume 32. No3. P.23-39.
4. Martinovich G.G., Cherenkevich S.N., Denisov A.A., Molchanov P.G., Gleb S.P. Modification of calcium homeostasis in model C6 and PC12 cells under oxidative stress // Vesti NAS Belarus. Ser. honey-b_yal. navuk. 2002. No. 4. C.70-76.
5. Kukcharenko L.V., Fuch H., Ilyich G.K., Gronskaya R.I., Cherenkevich S.N., Martinovich G.G. Scanning Force Microscopy Study of PC12 Cells Surface Morphology // Phys. Low- Dim. Struct. 5/6 (2002). Pp.115-120.
6. Martinovich G.G., Cherenkevich S.N., Denisov A.A., Molchanov P.G., Bulay P.M. Electrical activity of isolated ganglia of the mollusk Lymnaea stagnalis under the action of hydrogen peroxide // Vestn. Belarusian. un-that. Ser. 2. 2003. No. 3. C.17-23.
7. Martinovich G.G., Cherenkevich S.N. Intracellular effective redox potential & ndash; new factor of regulation of cellular processes // Vestn. Belarusian. un-that. Ser. 1. 2004. No. 1. C.28-36.
8. Martinovich G.G., Cherenkevich S.N. Redox buffer capacity of biosystems // Vestn. Belarusian. un-that. Ser. 1. 2004. No. 3. C.14-19.
9. Cherenkevich S.N., Martinovich G.G., Drapeza A.I., Martinovich I.V., Loban V.A., Lisichenok A.N. Cell technologies and their application in medicine // Healthcare. 2004. No6, P.26-32.
10. Martinovich G.G., Cherenkevich S.N. Utilization of hydrogen peroxide by epithelial cells of the human amnion // Biomedical chemistry. 2005. Vol.51. No. 6. P.626-633.
11. Martinovich G.G., Cherenkevich S.N., Sauer H. Intracellular redox state: towards quantitative description // Eur. Biophys. J. 2005. Vol. 34. No. 7. P. 937-942.
12. Cherenkevich S.N., Martinovich G.G. Reactive oxygen species and regulation of cellular functions // Vestn. GrSU them. I. Kupala. Series 2. 2008. No. 1. & ndash; P.109-117.
13. Martinovich G.G., Martinovich I.V., Cherenkevich S.N. Signal transduction with the participation of calcium ions in BGM and C6 cells under the action of hydrogen peroxide // Vestn. GrSU them. I. Kupala. Series 2. 2008. No. 3. C.150-155.
14. Martinovich G.G., Cherenkevich S.N. Redox homeostasis of cells // Advances in physiological sciences. 2008, volume 39, №3, pp. 29-44.
15. Martinovich G.G., Martinovich I.V., Cherenkevich S.N. Quantitative characteristics of the redox state of erythrocytes // Biophysics. 2008, volume 53, no. 4, pp. 618-623.
16. Martinovich G.G., Martinovich I.V., Cherenkevich S.N. Effects of ascorbic acid on calcium signaling in tumor cells // Bull Exp. Biol. Med. 2009. Vol.147, No. 4, P.469-472.
17. Martinovich G.G., Martinovich I.V., Golubeva E.N., Cherenkevich S.N. The role of hydrogen ions in the regulation of the redox state of erythrocytes // Biophysics. 2009, volume 54, no. 5, pp. 846-851.
18. Cherenkevich S.N., Martinovich G.G., Martinovich I.V., Golubeva E.N. Redox homeostasis of biological systems: theory and experiment. // Journal of the State Medical University. 2009. No. 2, p. 9-11.
19. Martinovich G.G., Martinovich I.V., Cherenkevich S.N., Sauer H. Redox buffer capacity of the cell: theoretical and experimental approach // Cell Biochem Biophys. 2010. Vol.58, No.2, P.75-83.
20. Shamova E.V., Gorudko I.V., Drozd E.S., Chizhik S.A., Martinovich G.G., Cherenkevich S.N., Timoshenko A.V. Redox regulation of morphology, cell stiffness, and lectin-induced aggregation of human platelets // Eur Biophys J. 2011, Vol. 40. # 2. P. 195-208.
21. Martinovich G.G., Martinovich I.V., Cherenkevich S.N. Redox regulation of cellular processes: a biophysical model and experiment // Biophysics. 2011. Vol.56, No. 3, P.444-451.
22. Martinovich G.G., Martinovich I.V., Golubeva E.N., Cherenkevich S.N., Demidchik Yu.E., Gain Yu.M., Vladimirskaya T.E., Lushchik M.L. Redox biotechnology as a basis for a new strategy in anticancer therapy // Izvestia of the National Academy of Sciences of Belarus. Ser. honey. sciences. 2012. No. 2. P.85-104.
23. Martinovich G.G., Golubeva E.N., Martinovich I.V., Cherenkevich S.N. Redox regulation of calcium signaling in cancer cells by ascorbic acid involving the mitochondrial electron transport chain // Journal of Biophysics, vol. 2012, Article ID 921653
24. Cherenkevich S.N., Martinovich G.G., Martinovich I.V., Gorudko I.V., Shamova E.V. Redox regulation of cellular activity: concepts and mechanisms // Bulletin of the National Academy of Sciences of Belarus. Ser. biol. sciences. 2013. No. 1. P.92-108.
25. Martinovich G.G., Martinovich I.V., Zenkov N.K., Menshchikova E.B., Kandalintseva N.V., Cherenkevich S.N. Phenolic antioxidant TS-13 regulating ARE-driven genes induces tumor cell death by a mitochondria-dependent pathway // Biophysics. 2015. Vol.60, No. 1, P.94-100.
26. Martinovich G.G., Martinovich I.V., Menshchikova E.B., Zenkov N.K., Cherenkevich S.N. Redox properties of tumor cells and their proliferative activity under the action of phenolic antioxidants // Reports of the National Academy of Sciences of Belarus. 2015. Vol.59, No. 3. P.82-87.
27. Zenkov N.K., Chechushkov A.V., Kozhin P.M., Kandalintseva N.V., Martinovich G.G., Menshchikova E.B. Plant phenols and autophagy // Biochemistry (Moscow). 2016, Vol. 81, No. 4, R. 297-314.
28. Martinovich G.G., Martinovich I.V., Vcherashnaya A.V., Shadyro O.I., Cherenkevich S.N. Differential regulation of the production of reactive oxygen species and mechanisms of tumor cell death by para-benzoquinones // Reports of the National Academy of Sciences of Belarus. 2016. Volume 60. No5, p. 96-100.
29. Martinovich G.G., Martinovich I.V., Vcherashniaya A.V., Shadyro O.I., Cherenkevich S.N. Thymoquinone, a biologically active component of Nigella sativa, induces mitochondrial production of reactive oxygen species and programmed death of tumor cells // Biophysics. 2016, Vol. 61, No. 6, pp. 963 & ndash; 970.
30. Zenkov N.K., Chechushkov A.V., Kozhin P.M., Kandalintseva N.V., Martinovich G.G., Menshchikova E.B. Mazes of Nrf2 Regulation. // Biochemistry (Moscow). 2017, Vol. 82, No. 5, R. 556-564.
31. Martinovich G.G., Martinovich I.V., Vcherashniaya A.V., Zenkov N.K., Menshchikova E.B., Kandalintseva N.V., Cherenkevich S.N. Mechanisms of redox regulation of chemoresistance in tumor cells by phenolic antioxidants. // Biophysics. 2017. Vol. 62, No.6, pp.942-949.
32. Gainutdinov P.I., Kozhin P.M., Chechushkov A.V., Martinovich G.G., Holshin S.V., Kandalintseva N.V., Zenkov N.K., Menshchikova E.B. An inverse relationship between the antioxidant activity of synthetic monophenols of a structurally related series and their toxicity towards tumor cells. // Siberian Scientific Medical Journal. 2018. Volume 38. No1, pp. 22-31.
33. Martinovich G.G., Martinovich I.V., Vcherashnaya A.V., Zenkov N.K., Menshchikova E.B., Cherenkevich S.N. Regulation of proliferative activity and chemoresistance of tumor cells with sodium ascorbate. // Dokl. Nat. acad. sciences of Belarus. 2018.Vol. 62.No. 1, p. 93 & ndash; 100.
34. Martinovich G.G., Martinovich I.V., Vcherashnaya A.V., Zenkov N.K., Menshchikova E.B., Cherenkevich S.N. Biophysical and molecular mechanisms of redox regulation of chemoresistance of tumor cells // Actual problems of biological physics and chemistry. 2018. Volume 3. No. 2, pp. 379-383.
35. Menshchikova E.B., Zenkov N.K., Kozhin P.M., Chechushkov A.V., Kovner A.V., Khrapova M.V., Kandalintseva N.V., Martinovich G.G. Synthetic phenolic antioxidant TS-13 suppresses the growth of Lewis lung carcinoma and potentiates oncolytic effect of doxorubicin // Bulletin of experimental biology and medicine, 2019, Vol. 166, No. 5, pp. 646-650.
36. Zenkov N.K., Kozhin P.M., Yesterday A.V., Martinovich G.G., Kandalintseva N.V., Menshchikova E.B. Features of redox regulation in tumor cells // Siberian Scientific Medical Journal. 2019, Volume 39. No. 9, pp. 11-26.
37. Menshchikova E.B., Chechushkov A.V., Kozhin P.M., Kholshin S.V., Kandalintseva N.V., Martinovich G.G., Zenkov N.K. Activation of Autophagy and Nrf2 Signaling in Human Breast Adenocarcinoma MCF-7 Cells by Novel Monophenolic Antioxidants // Cell Tiss. Biol. 2019, Vol. 13, No. 2, P. 85-92.
38. Zenkov N.K., Chechushkov A.V., Kozhin P.M., Martinovich G.G., Kandalintseva N.V., Menshchikova E.B. Autophagy as a defense mechanism against oxidative stress. Bulletin of Siberian Medicine. 2019, Volume 18.No.2, pp. 195-214.
39. Zenkov N.K., Kozhin P.M., Chechushkov A.V., Kandalintseva N.V., Martinovich G.G., Menshchikova E.B. Oxidative stress during aging // Advances in gerontology. 2020.Vol. 33, No. 1. P. 10 & ndash; 22.
40. Vcherashniaya A.V., Martinovich I.V., Martinovich G.G., Shadyro O.I., Cherenkevich S.N. A Raman Spectroscopic Study of Thymoquinone Antitumor Action. // Journal of Applied Spectroscopy. 2020. Vol. 87, No. 3.P. 515-519.
41. Martinovich G.G., Martinovich I.V., Vcherashnaya A.V., Zenkov N.K., Menshchikova E.B., Cherenkevich S.N. Chemosensitization of tumor cells by phenolic antioxidants: the role of the Nrf2 transcription factor // Biophysics. 2020. Volume 65, No. 6. pp. 1081-1092.
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